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News items December 2020

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Creative Diagnostics Launches Its IHC Antibodies for Pathology
Creative Diagnostics Launches Its IHC Antibodies for Pathology
As a global leading supplier of of raw materials, antibodies, and reagents for bio-technology industry, Creative Diagnostics announces the introduction of a variety of IHC antibodies for pathology research usage. A number of high quality pathology recombinant monoclonal antibodies including Her2, PD-1, Ki-67, Tim3, CTLA4, Lp-PLA2, Muc2, Cytokeratin 18, BRAF V600E, IDH1 R132H, MLH1, MSH2, MSH6, and PMS2 are developed by Creative Diagnostics and are available now. These new antibodies have been extensively tested and validated for immunohistochemistry on human tissues and are engineered to deliver consistent, specific, and sensitive stains. Creative Diagnostics` IHC antibodies have been characterized at different concentrations against normal human or diseased tissues and additional relevant controls, and are presented as prediluted format as well as concentrated format. FSH monoclonal antibody(CABT-L2883), the pathology antibody for immunohistochemistry use for instance,
31-12-2020  |  101x  |  Product news  | 
What Everybody Ought To Know About Fluorescent Polymers
In recent years, there are huge demands for fluorescent materials, as they play important roles in various research areas such as chemistry and biology. Due to their fascinating properties and important applications in the fields of materials and life sciences, the research on fluorescent polymers has also attracted extensive scientific attention. In September 2020, polymer researchers from the University of Southern Mississippi, in collaboration with other scientists, have developed fluorescent solids and according to their research, they said that to be the brightest known materials in existence. Their discoveries may be potentially applied in everything from solar energy to medical diagnostics and lasers, and even in autonomous cars. More studies are on the way to find more about the fluorescent polymers for their potential applications. So what exactly are these polymers? What Are Fluorescent Polymers? Fluorescent polymers are functional macromolecules with various
31-12-2020  |  101x  |  Industry news
Matexcel Provides Photovoltaic Product Analysis Service to Promote R&D
Matexcel Provides Photovoltaic Product Analysis Service to Promote R&D
Matexcel, a leading service provider in material science, offers photovoltaic product analysis services, including photovoltaic module analysis, photovoltaic product non-destructive analysis, and photovoltaic raw material analysis to help promote independent R&D progress. Photovoltaic products refer to products that use solar cells to convert light into electricity. Broadly speaking, photovoltaic products refer to products that use the current generated by the photovoltaic effect as energy sources, such as solar street lights, traffic lights, marking lights, navigation marks, etc. In a narrow sense, photovoltaic products refer to photovoltaic cell modules, components and photovoltaic power generation systems. Now, photovoltaic products are not only limited to solar cells. For example, our more common photovoltaic products include: rural photovoltaic power generation systems, solar power system equipment, photovoltaic power supplies/batteries, photovoltaic seawater
29-12-2020  |  088x  |  Product news  | 
Boc rna launches the Latest Message for RNAi Delivery Technology Coope
Boc rna launches the Latest Message for RNAi Delivery Technology Coope
Recently, Boc rna announced the expansion of its existing cooperation scope, including the development and commercialization of RNAi therapeutic drugs. The company will use its latest progress in targeted delivery of siRNA drugs and its established capabilities to deepen the development of RNAi drugs for tumors and neurological diseases. Safe and effective siRNA delivery has always been a key challenge in the field of therapeutic RNAi. The siRNA conjugate delivery platform developed by Boc rna scientists can overcome this challenge. "This technology is different from the lipid nanoparticle siRNA delivery system used by most RNAi therapy companies. And we believe that this will be one of the most promising solutions in the field of RNAi therapy." said Dr. Sarah, Chief Scientist of Boc rna drug Delivery Platform. siRNA conjugation modification is a customizable and powerful tool that can solve the problem of RNAi delivery and can create a variety of new therapies. This
28-12-2020  |  056x  |  Product news  | 
BOC Sciences Lanuched A New Enzyme Labeling Platform
BOC Sciences Lanuched A New Enzyme Labeling Platform
Recently, BOC Sciences, a well-known chemical and pharmaceutical supplier, announced the launch of a new enzyme labeling technology platform for the scientific community. Enzyme labeling is a method to place chemical markers on the molecules of substances in bioanalysis. Molecular markers allow the detection and tracking of molecules in substances during chemical analysis or testing. Different types of tags can be used for this type of biolabeling. When an enzyme chemically binds to another molecule, the process is called enzyme labeling. Although great progress has been made in the detection of fluorescent and luminescent labels, enzymes are still the most sensitive reporter molecules. For most applications, direct enzyme labeling provides the best overall performance, highest sensitivity, least background and rapid detection. Enzymes such as horseradish peroxidase (HRP) or alkaline phosphatase (ALP) can bind to antibodies, oligonucleotides, peptides or proteins and
28-12-2020  |  085x  |  Industry news  | 
Alfa Chemistry Recently Launched a Sub-website for Functional Polymers Alfa Chemistry Functional Polymers
Alfa Chemistry Recently Launched a Sub-website for Functional Polymers
Alfa Chemistry Functional Polymers In December, 2020, the US-based chemical supplier Alfa Chemistry announced the launch of a new sub-website for the supply of functional polymers, including Adsorptive Polymers, Biomedical Polymers, Electrofunctional Polymers, Functional PEGs, Photoactive Polymers, Silicone Polymers and more. With unstopping efforts, the company continues to offer chemicals for specialized applications, such as catalysts, fatty acids, analytical reagents, materials, and MOF chemicals. Functional polymer is a special type of polymer in which the polymer chain contains one or more reactive groups attached to the chain end or main chain. Polymers are traditionally used in plastics, rubber, and coatings. Owing to the advances of modern synthetic polymer chemistry, varieties of functional polymers have been developed for various applications including optoelectronics, catalysis, biomaterials, medicine, building materials, water treatment, coatings, and many more. Functional materials are
28-12-2020  |  075x  |  Industry news  | 
Alfa Chemistry Newly Launches a Subsidiary of Fatty Acids Alfa Chemistry Fatty Acids
Alfa Chemistry Newly Launches a Subsidiary of Fatty Acids
Alfa Chemistry Fatty Acids Fatty acids are precursors of essential substances in the body. Defects in fatty acid metabolism will result in diseases. For scientists and researchers who are engaged in fatty-acid-related diseases, Alfa Chemsitry newly launches a subsidiary website, supplying varieties of fatty acids to support their research projects. Now Alkyl Methane Sulfates, Cholesterol, Fatty Acetates, Glycerides and many other fatty acids can be easily found at Alfa Chemistry. Fatty acids are carboxylic acids with long aliphatic chains. They are important dietary sources of fuel for animals and also are important structural components for cells. Fatty acids usually exist as three main classes of esters: triglycerides, phospholipids, and cholesteryl esters, and can be divided into four general categories: saturated, monounsaturated, polyunsaturated, and trans fats. “Fatty acids play multiple roles. First, they are constituents of phospholipids which are the “building blocks” of cell membranes.
28-12-2020  |  068x  |  Industry news  | 
Creative Biostructure Released Target 3D Structure Analysis Service
Creative Biostructure Released Target 3D Structure Analysis Service
Creative Biostructure, a biotech company specialized in providing cost-effective contract services related to structural biology and membrane protein technologies to both academia and biotech/pharmaceutical industries, now released target 3D structure analysis service for drug discovery. Target structure information can be used in multiple links of drug discovery, such as target selection, identification and optimization of hit points, development of final properties of compounds using multithreading processes and reconstruction of biological macromolecular structures by rational design to optimize their structural druggability. Moreover, the high drug consumption rate associated with clinical trials in the late stages of drug development is an important reason for the rising cost, which further promotes the need to obtain accurate target three-dimensional (3D) structural information to reduce the possibility of drug failure. Using extensive expertise in structural
25-12-2020  |  053x  |  Product news  | 
MedAI: Explore Therapeutic Antibody Discovery and Development
MedAI: Explore Therapeutic Antibody Discovery and Development
Bio-drugs are more extensively used in disease treatment, especially in the past decade. On December 22, 2020, MedAI, an expert of AI-assisted R&D research company, announces that it now provides AI-driven solutions for the development of therapeutic antibodies, which could be used for the treatment of pathologies such as oncology. The introduction and application of AI would greatly help scientists and researchers find solutions in a faster and more precise way, and at the same time help reduce the R&D costs. “The objective of MedAI is to propose a software suite that can create a formal approach of antibody development,” commented the representative speaker from MedAI. “We believe with AI system, the risks of failure will be decreased, the duration of pre-clinical steps will be shortened, and the intellectual protection will also be strengthened.” In short, the protein or antibody drug discovery and development is the process of identifying new therapeutic antibodies
24-12-2020  |  038x  |  Product news  | 
AI Assists in Therapeutic Monoclonal Antibodies Development
AI Assists in Therapeutic Monoclonal Antibodies Development
Since 1985, about 100 independent monoclonal antibodies (mAb) have been developed for use as drugs. mAb is a homogeneous preparation of antibodies (or antibody fragments). The protein sequence of each antibody in the product is the same. Therefore, it is expected that the antigen recognition site, affinity, biological interaction and downstream biological effects of each antibody are the same. This distinguishes mAbs from polyclonal antibodies, which have heterogeneous protein sequences and recognize different epitopes on the same antigen. Some basic facts about therapeutic monoclonal antibodies Technology is used to modify and mass-produce mAbs, so that they can be used as therapeutic drugs in patients. Initial antibody selection-the key to determining the effectiveness of mAbs is the quality of the interaction between the hypervariable region and the target antigen, also known as complementarity-determining region (CDR). The selection of target antigens is usually
24-12-2020  |  040x  |  Industry news  | 
Application of artificial intelligence in drug development
Application of artificial intelligence in drug development
Through machine learning, evolutionary computing, image recognition, natural language processing and cognitive computing, artificial intelligence (AI) can be applied in the following fields: Drug Targets Development, Drug Mining, Compound Screening, Predication of ADMET Properties, Crystal Structure Prediction, Pathophysiology, and Drug Repurposing. Target drug development The key to research and development of new drugs is to find, determine and prepare drug targets. Drug targets refer to the binding sites of drugs in the body, including biological macromolecules, such as loci, receptors, enzymes, ion channels and nucleic acids. Identifying new and effective drug targets is the top priority of new drug development. Therefore, the work involved in discovering and verifying a large number of molecular targets has greatly increased the burden of drug development. Machine learning algorithms can be fully applied to the old single-target drug discovery project. Researchers
24-12-2020  |  051x  |  Industry news  | 
New Drug Combination Could Control Blood Sugar and Weight In Diabetes
New Drug Combination Could Control Blood Sugar and Weight In Diabetes
Scientists have shown that adding an experimental cancer drug to a widely used diabetes treatment improves blood sugar control and weight loss in mice, according to a study published on 22nd, Dec. in eLife. The results pave the way for clinical studies of the new drug combination as a more effective long-term treatment for millions of people with diabetes and obesity. Glucagon-like peptide 1 agonists (GLP-1 analogs) are a relatively new class of drugs that reduce blood sugar levels and lower body weight. They partially function by binding to the glucagon-like peptide 1 receptor on pancreatic beta cells, which leads the cells to produce insulin. But not all patients achieve normalization of blood glucose control with GLP-1 drugs, and very few achieve full reversal of obesity. "We have previously shown that prolonged association of the GLP-1 agonists with the glucagon-like peptide 1 receptor supports insulin secretion in pancreatic beta cells," explains project team
24-12-2020  |  066x  |  Industry news  | 
Creative BioMart Supports Protein Research with a Complete Set of Prot
Creative BioMart Supports Protein Research with a Complete Set of Prot
Creative BioMart, with years of experience and advanced technologies, supports protein research with a complete set of protein engineering services from a starting point of gene information to final optimized proteins. The protein engineering field is expanding rapidly for the last two decades in both the industrial and health care sectors. The main purpose of protein engineering is to identify specific changes in the amino acid sequence and to alter this sequence for desired functional properties. Generally, two approaches have emerged in protein engineering: computational simulation based on modern computer technology, called rational design, and experimental/molecular methods based on natural topics of evolution, called directed evolution. Based on the availability of studies on sequence-structure relationships, researchers apply rational design or directed evolution, or a combination of both, to obtain proteins with desired properties. Backed by years of experience
24-12-2020  |  063x  |  Product news  | 
Various Diagnostics Kits for Plant Pathogens Now Available at Lifeasib
Various Diagnostics Kits for Plant Pathogens Now Available at Lifeasib
Lifeaible, a biotech company that provides a variety of agro-related services and products for environmental and energy solutions, now offers a wide range of diagnostic kits for the detection of different plant pathogens. Plant pathogens include fungi, bacteria, nematodes, viruses, and all organisms that can cause disease symptoms and significantly reduce productivity, quality, and even death of plants. Pathogens can be introduced and spread to host plants in a variety of ways. Bacteria and fungal spores can be transferred by wind, rain, and can also be transferred from soil to plant tissues by rain. When insects feed on infected host plants, and then feed and eat on uninfected plants, they can serve as vectors for pathogens to infect plants. Pathogens can also be spread through infected seeds, transplanted or contaminated equipment, irrigation water, and humans. To minimize the losses caused by plant pathogens, a critical step is to detect pathogens in early stage.
24-12-2020  |  053x  |  Product news  | 
New Nanoparticle Can Kill Cancer Cells Efficiently And Selectively
New Nanoparticle Can Kill Cancer Cells Efficiently And Selectively
Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have developed a novel type of nanoparticle that efficiently and selectively kills cancer cells, thus opening up new therapeutic options for the treatment of tumors. Many chemotherapeutic agents used to treat cancers are associated with side-effects of varying severity, because they are toxic to normal cells as well as malignant tumors. This has motivated the search for effective alternatives to the synthetic pharmaceuticals with which most cancers are currently treated. The use of calcium phosphate and citrate for this purpose has been under discussion for some years now, since they lead to cell death when delivered directly into cells, while their presence in the circulation has little or no toxic effect. The problem consists in finding ways to overcome the mechanisms that control the uptake of these compounds into cells, and ensuring that the compounds act selectively on the cells one wishes to eliminate. Researchers
24-12-2020  |  050x  |  Product news  | 
Alfa Chemistry Releases Nanomaterials for Various Applications Alfa Chemistry Materials
Alfa Chemistry Releases Nanomaterials for Various Applications
Alfa Chemistry Materials The past decade has seen an impressive growth of nanotechnogy. Nanomaterials are widely used in many areas such as drug delivery, cell tracking, and regenerative medicine. To better cater to the market demand, Alfa Chemistry Materials, an expert in specialized materials, announces to release varieties of nanomaterials for customers worldwide on December 22, 2020. Nanomaterials are characterized by their tiny size, which is measured by nanometers. A nanometer is one millionth of a millimeter. The small size makes the material both promising and challenging. Their properties such as size, shape, high reactivity and other unique characteristics make nanomaterials potentially beneficial in product development and drug delivery, but may also cause some biological and environmental concerns. With the continuous effort of researchers around the world, nanotechnology persists to develop solutions in cosmetics, technology, medicines, and tools that benefit our daily life both
23-12-2020  |  034x  |  Product news  | 
Alfa Chemistry Sorts Out Trending Products for Christmas Season
Alfa Chemistry Sorts Out Trending Products for Christmas Season
To express sincere gratitude to customers for their support and trust, Alfa Chemistry announces to have sorted out a list of popular trending products and offers a discount for those chemicals during the Christmas season. Almost all of them are in stock and can be delivered to buyers within 5-7 business days. The quality chemicals supplied by Alfa Chemistry are of various kinds, including Boronic Compounds, Chemical Fluorescence Probe, Dyes, Fluorinated Building Blocks, Heterocyclic Organic Compound, Insect Pheromone, Ionic Liquids, Material & Chemicals, Metal Organics, Nanomaterials, Optoelectronic Materials, Organic Building Blocks, PEG linkER, Plant Extract, Precious Metal Catalyst, Single Crystals, Steroidal Compounds, and Surfactant. Some can be used for academical research purpose, while a portion of them can be used for industrial manufacturing. “For products that are not available on the market, we also provide customized projects to synthesize the desired
23-12-2020  |  038x  |  Industry news  | 
Alfa Chemistry: Instrumental Analytical Reagents Are Now Accessible
Alfa Chemistry: Instrumental Analytical Reagents Are Now Accessible
On December 17, 2020, Alfa Chemistry announces in a statement that the company starts to provide varieties of instrumental analytical reagents for consumers worldwide. In addition to other reagents that are previously released, now the company’s supply range of products are widely broadened, which encompasses: chromatography standards and derivatization reagents, Ion Sensor Materials, Laboratory Supplies, LPLC/TLC/Paper Chromatography, and Titration. Although there are many types of analytical reagents, different analytical reagents are used for varied analytical testing purposes. Some reagents are testing items specially used for chemical reaction analysis, such as baseline reagent and indicator, while instrumental analytical reagents are specially used when testing instruments are used. They are high-purity compounds dedicated to instrumental analysis. “Alfa Chemistry`s product line of instrumental analytical reagents includes chromatography reagents & solvents,
23-12-2020  |  036x  |  Product news  | 
Pesticide Residue Analysis Now Available at Alfa Chemistry Testing Lab
Pesticide Residue Analysis Now Available at Alfa Chemistry Testing Lab
On December 17, 2020, Alfa Chemistry Testing Lab, a cGMP-compliant laboratory of Alfa Chemistry, announced that pesticide residue analysis is now available. With extensive experience in the analytical testing field, the lab is capable of conducting analysis of various foods that might contain pesticide or herbicide such as raw agricultural products, processed agricultural products, soil, plant and water. As food and soil safety has become a top concern in the recent decade, strict international regulations on maximum residue limits are established. And thanks to the advances of analytical chemistry, now automated high-throughput analytical methods such as iquid chromatography-mass spectrometry (LC-MS) have made it easier to identify and quantify residues in food. “The purposes of setting maximum residue limits for food commodities are to protect consumers from exposure to unhealthy pesticide or herbicide residue levels and also to facilitate the international food
23-12-2020  |  031x  |  Product news  | 
Stainless steel laboratory furniture Very suitable for use in cleanrooms
Stainless steel laboratory furniture
Very suitable for use in cleanrooms New offer at LabMakelaar: Diverse range of stainless steel laboratory furniture, very suitable for use in cleanrooms. LabMakelaar Benelux B.V. strives for a world with a strong circular economy, in which companies have easy access to a total solution for furnishing and equipment for their laboratory with high-quality and recycled material. Are you looking for affordable laboratory equipment and lab furniture? LabMakelaar Benelux B.V. is the specialist for inexpensive used laboratory equipment. From (design) fume cupboard to laboratory table. From powder fume cupboard to Biohazard safety cupboard.
22-12-2020  |  050x  |  Industry news  | 
LabForRent: 243 m2 net of laboratories Bèta building, High Tech Campus Eindhoven (NL)
LabForRent: 243 m2 net of laboratories
Bèta building, High Tech Campus Eindhoven (NL) Twice: Building high tech success Total 243 m2 net of laboratories divided over 6 laboratories. These can be rented individually or together. In addition, there are various options for office spaces. Twice has made various electrotechnical and mechanical laboratories available in its Science hub on the High Tech Campus. A total of approximately 250m2 net of laboratories is available, divided over six contiguous laboratories, with various options for renting office space. The laboratories are equipped with extensive options, including anti-static floors, three-phase power, emergency power, extraction, compressed air, vacuum and process water. Because the laboratories are available turn-key and can also be individually locked, Bèta is also extremely suitable for smaller companies, setups and (temporary) projects. Twice is a link in a large network that can support the growth of a company. Together with our shareholders (TU/e, Municipality of Eindhoven, BOM, Brainport
22-12-2020  |  056x  |  Industry news  | 
Genome Editing In Plant—Targeted Modification of The Genome
By transferring genes or genetic elements with known functions to superior crop varieties, genetically modified (GM) crops with beneficial properties can be produced. Despite the promise that GM crops can contribute to global food security, the use of GM crops is affected by largely unproven health and environmental safety issues. The government regulatory framework aimed at maintaining human and environmental biosafety has created a huge cost barrier to the rapid and widespread adoption of new genetically modified properties. As a result, the advantages of transgenic properties have been limited to a few cultivated crops. Genome editing is defined as a collection of advanced molecular biology techniques that facilitate precise, efficient and targeted modification of genome sites. The risks involved in changing the genome through the use of genome editing techniques are significantly lower than those associated with genetically modified crops, because most edits only
16-12-2020  |  084x  |  Industry news
Guide to Figure out The Application Prospects of Crispr gene Editing
In a recent study, researchers at the Massachusetts Institute of Technology`s Bode Institute and Harvard University programmed a CRISPR-related enzyme to target three different single-stranded RNA viruses in human embryonic kidney cells ( as well as human lung cancer cells and dog kidney cells) are grown in vitro and minced so that they are largely incapable of infecting other cells. If further experiments indicate that the process is effective for living animals, it may eventually help to identify new antiviral therapies for diseases such as human Ebola or Zika disease. CRISPR is a gene editing technology, a "molecular scissors" that allows scientists to "cut" and "paste" genes into DNA and perform gene editing faster and more accurately. Based on a targeted DNA destruction defense system originally discovered in certain prokaryotes, CRISPR has revolutionized medical science by introducing easy-to-use genome modification methods. CRISPR plays an important role in
16-12-2020  |  079x  |  Industry news
The Workflow of miRNA Expression Plasmids and Its Wide Application
MicroRNAs (miRNAs) are naturally occurring 21-23 nt noncoding RNAs that are involved in many biological processes and disease development. They have been found in all species and regulates the translation and degradation of its target messenger RNA by binding to complementary regions in mRNA. Creative Biogene provides a comprehensive miRNA expression plasmids covering human, mouse, and rat genomes to detect the effects of miRNAs on cell functions and phenotypes. These vectors provide powerful miRNA expression and allow scientists to validate and track the expression using fluorescent protein markers. In addition, we also offer cloning services to design the most suitable custom products according to specific needs. The miRNA clone insert of Creative Biogene consists of pri-mir (60-70nts) and 250-300nts genomic sequences flanking it. In general, flanking sequences are required for correct pri-mir expression and mature microRNA processing. To test miRNA expression, isolate
16-12-2020  |  082x  |  Industry news
Creative Enzymes Releases Enzymes for Food and Beverage Industry
Creative Enzymes Releases Enzymes for Food and Beverage Industry
Creative Enzymes, an excellent supplier and manufacturer located in New York, always hammers at researches and trials in order to provide customers with various enzymes as many as possible. These days, the product manager of Creative Enzymes announces that the company has recently released enzymes in food and beverage industry, which can be readily used in food and beverage processes. “We are happy to declare that we have launched the enzymes for food processing, these products will have a better market prospect based on large demands and their specific features.”said senior scientist at Creative Enzymes. Creative Enzymes provides four enzymes for food processing, including fruit and vegetable processing enzymes, baking enzymes, brewing enzymes, starch & sweeteners enzymes. Enzymes are known to aid food processing in a wide variety of applications, for example, manufacturing of cheese, vinegar and wine; leavening of bread; brewing of beer and so on. In these processes,
15-12-2020  |  095x  |  Product news  | 
CD Genomics Optimized NGS Oncology Panels for Cancer Related Research
CD Genomics Optimized NGS Oncology Panels for Cancer Related Research
With a high reputation for sequencing, microarray analysis, library construction and genotyping, CD Genomics provides reliable services to pharmaceutical and biotechnology companies as well as academia and government agencies. These days, the product manager of CD Genomics announced that the company has recently optimized NGS oncology panels, which can meet the most challenging research processes. Cancer is a genetic disease, which is induced by the accumulation of harmful DNA mutations in cells. At present, it has been elucidated that the mechanisms of inducing abnormal cell proliferation, differentiation, and cancer production are mainly categorized as follows: activating dominant transforming proto-oncogenes by translocations and mutations, inactivating tumor suppressor gene by mutations, and disordering the DNA repair genes. There are two basic types of gene mutations, namely germline mutations and somatic mutations, depending on where the mutation occurs in the
15-12-2020  |  081x  |  Product news  | 
Food Microbiology Testing Service to Ensure the Food Safety
Food Microbiology Testing Service to Ensure the Food Safety
Creative Proteomics is an integrated CRO company committed to providing proteomics and metabolomics services. The Foodtest division is affiliated with Creative Proteomics, which aims to provide high-quality analytical services to customers in the academic, healthcare and food industries. These days, Foodtest division of Creative Proteomics has recently launched its fully-developed food microbiology testing service to ensure the safety and quality of food products, reducing the health risk to humans and the economic loss caused by foodborne outbreaks. Microbiological testing of pathogens and spoilage bacteria is a key step to ensure food safety and quality, reduce human health risks and economic losses caused by foodborne disease outbreaks. Microbiological testing is used to ensure that raw materials and final products meet required specifications, identify risk factors or confirm compliance with regulations. The infectious dose of many harmful microorganisms is very
15-12-2020  |  115x  |  Industry news  | 
The Application of Induced Pluripotent Stem Cells in Stem Cell Researc
Induced pluripotent stem cells (iPSC) can self-renew indefinitely in culture and differentiate into all specialized cell types, including gametes. iPSC does not exist naturally, but is produced from somatic cells ("induced" or "reprogrammed") in culture through ectopic co-expression of determined pluripotency factors. Since they can be produced from any healthy person or patient, iPSCs are regarded as a valuable resource for regenerative medicine to replace diseased or damaged tissues. In addition, reprogramming technology provides powerful tools for studying cell fate determination mechanisms and simulating human diseases, thereby greatly enhancing the possibility of discovering new drugs in the form of screening and treating life-threatening diseases through cell therapies based on strategies. Human iPSC is in many diseases that cannot be cured or effectively treated, such as neurodegenerative diseases of the central nervous system, heart disease, diabetes, and liver,
15-12-2020  |  043x  |  Industry news
Analysis on The Revolutionary Progress of Stem Cell Technology
Stem cell technology, also known as regenerative medicine, new, normal or even younger cells, tissues or organs are bred in vitro by separating stem cells, in vitro culture, directed induction, and even genetic modification, and ultimately the treatment of clinical diseases is achieved by transplantation of cells, tissues or organs. The application of stem cells to treat diseases is no longer just an idea. Although the research time of stem cells is limited, it has begun to enter the clinical trial stage with its treatment of diseases. Recently, the New England Journal of Medicine published a study achieved by Chinese scholars which is the first time in the world to use gene editing methods to inactivate CCR5 gene in human hematopoietic stem cells and transplant the edited stem cells into HIV (HIV) infection combined with acute lymphoblastic leukemia. Gene-edited hematopoietic stem cells can survive and multiply in patients, becoming the key to curing AIDS. The researchers
15-12-2020  |  040x  |  Industry news
The Role of Exosomes in Biological Research And Cancer Treatment
Exosomes, as the small particles of endosomal-derived lipid bilayers, that are a subset of extracellular vesicles (EVs) secreted by most cell types. Due to the emerging role of exosomes as intercellular messengers and their potential in disease diagnosis, the interests in exosome research have grown over the past decade. Indeed, exosomes contain proteins, lipids and RNA specific to their cellular origin that can transport cargo to nearby and distant cells. As a result, investigations into foreign goods can provide opportunities for disease detection and treatment. Furthermore, since exosomes can be safely transported in extracellular fluids and deliver cargos to designated cells with high specificity and efficiency, they have been explored as natural drug delivery vehicles. Despite tremendous efforts in this relatively new field of research, progress has been hampered by challenges such as inefficiencies in separation methods, difficulty in characterization, and lack
15-12-2020  |  059x  |  Industry news
EKF introduces accurate quantitative COVID-19 antibody test kit COVID-SeroKlir SARS-CoV-2 IgG test kit detects presence and precise levels of COVID-19 neutralising antibodies
EKF introduces accurate quantitative COVID-19 antibody test kit
COVID-SeroKlir SARS-CoV-2 IgG test kit detects presence and precise levels of COVID-19 neutralising antibodies EKF Diagnostics, the global in vitro diagnostics company, announces that it has introduced one of the first tests to precisely measure levels of COVID-19 neutralizing antibodies in individuals. Unlike other antibody tests, the Kantaro COVID-SeroKlir SARS-CoV-2 IgG antibody test kit determines both the presence and specific quantities of human IgG antibodies to the SARS-CoV-2 virus. This enables a broad range of COVID-19 applications, such as delivering vital knowledge for advancing the understanding of protective immunity, assessing vaccine response and accelerating therapeutic treatments. The high performance quantitative COVID-SeroKlir kit has received FDA Emergency Use Authorization (EUA) and is CE marked. It has demonstrated 98.8% sensitivity and 99.6% specificity for detecting SARS-CoV-2 specific IgG antibodies against two SARS-CoV-2 virus antigens, the full-length spike protein and its receptor-binding domain (RBD). This confirmed accuracy means false positives
15-12-2020  |  083x  |  Product news  | 
MassARRAY Systems for Cost-effective SNP Genotyping CD Genomics Announces MassARRAY Systems for Cost-effective SNP Genotyping
MassARRAY Systems for Cost-effective SNP Genotyping
CD Genomics Announces MassARRAY Systems for Cost-effective SNP Genotyping CD Genomics, an internationally leading provider of microbial testing services, microbial genomics services, and integrated bioinformatics services for hospitals, food, diagnostics, pharma, agriculture, biotechnology, and research institutes, announces advanced MassARRAY systems to provide customer with efficient and cost-effective SNP genotyping. The MassARRAY system is based on MALDI-TOF mass spectrometry. The PCR amplified product was added with SNP sequence-specific extension primers to extend 1 base at the SNP site. MassARRAY has been widely used in cancer research, genetic analysis, molecular diagnosis and pharmacy. The basic principle of the MassARRAY system is matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) technology, which has extremely high specificity and sensitivity. Time-of-flight mass spectrometry technology with different detection and software modules can realize the research or application of SNP genotyping,
14-12-2020  |  071x  |  Industry news  | 
COVID-19 winter lockdowns drive demand for ‘body & mind` formulations
Manufacturers seeking CDMOs that can quickly develop complex formulations offering both body and mind benefits 14 December, 2020: SIRIO Europe (Ayanda) – the European nutraceutical and pharmaceutical contract development and manufacturing organisation (CDMO) and member of SIRIO Group – forecasts a winter surge in requests from nutra brands for new ‘dual benefit’ mood enhancing formulations as a result of COVID-19 measures. The company said the normal winter increase in demand for mood enhancing formulations is being significantly accelerated by the ongoing effects of European and North American lockdowns and national restrictions. But rather than purchase these as stand-alone products, consumers are looking for nutraceuticals that also provide physical health benefits – including enhanced immunity, heart function or metabolism. Brands are increasing differentiating by marketing products with health benefits for ‘body and mind’ with ingredients that combine holistic wellness as well as mood enhancing properties. For example, combination products containing plant-based extracts,
14-12-2020  |  036x  |  Industry news
Automatic reproducible sieve stack tensioning system For exact results and can be attached and used with any sieve shaker
Automatic reproducible sieve stack tensioning system
For exact results and can be attached and used with any sieve shaker The universal sieve clamping system TorqueMaster enables automatic and reproducible tensioning of the sieve stack on the sieve shaker during dry sieving with test sieves 200 mm/8’’ diameter. Although the tensioning has a great influence on the sieving result, it is relatively undefined in conventional systems. With the electric and easy-to-use sieve stack tensioning system TorqueMaster you can deliver a constant and reproducible clamping forces of ~ 1 kN to the sieve stack, enabling the calibration of the sieve tensioning – essential when using your sieve shaker as an instrument for inspection according to ISO 9001. The sieve stack tensioning system TorqueMaster consisting of clamping lid plexiglas for test sieves 200 mm/8" dia. and electrical tool 100-240 V/1~, 50-60 Hz and can be combined with any sieve shaker. Standardized for integration into a quality management system according to ISO 9001 The high performance Vibratory Sieve Shaker Analysette 3 PRO offers everything
14-12-2020  |  066x  |  Product news  | 
A leading CRO`s digital data transformation: a case study Jubilant Biosys improves data management, research productivity, and customer satisfaction with CDD Vault
A leading CRO`s digital data transformation: a case study
Jubilant Biosys improves data management, research productivity, and customer satisfaction with CDD Vault Jubilant Biosys, an international contract research organisation (CRO), has provided drug discovery and contract research services to the global pharmaceutical industry for 20 years. “Our vision is to become a top 10 CRO/CDMO and deliver ‘the added dimension’ in discovery services,” said Marcel Velterop, President Drug Discovery Services and CDMO at Jubilant Biosys. “We symbolise this by our 4D brand, which promises to accelerate all aspects of both functional and integrated services to our innovative customers around the world. Introducing a digital agenda is a key part of this promise, and a range of initiatives have started, including CDD Vault ELN implementation.” Read the full article to learn how Jubilant Biosys realized a full suite of benefits by digitalizing data capture, management, and sharing.
14-12-2020  |  042x  |  Industry news  | 
COVID Moonshot - Data Coordination Strategy to Develop Antiviral
COVID Moonshot - Data Coordination Strategy to Develop Antiviral
The COVID Moonshot is a global consortium with the goal of rapidly developing antivirals for COVID-19. Dr. Lizbe Koekemoer of Oxford University describes how the project team leverages the CDD Vault informatics platform to effectively store, manage, and share data among multiple international partners.
14-12-2020  |  037x  |  Industry news  | 
Manual Thermal Desorption for Gas Chromatography HandyTD is an easy thermal desorption device for manual thermal desorption.
Manual Thermal Desorption for Gas Chromatography
HandyTD is an easy thermal desorption device for manual thermal desorption. HandyTD is an easy thermal desorption device for manual thermal desorption. The instrument has its own gas control, so there is no need to cut carrier lines from an existing gas chromatograph (GC). HandyTD has a needle that is inserted into the inlet of the host GC and a gas frow from the HandyTD will push the sample to the GC inlet. The colour display will guide the user to the operating steps. The size of the tubes used in the HandyTD are ¼ x 3½ inch, this is the size of the standard available thermal desorption tubes. Strong points Space-saving design In-house patented technology achieves a fast heating rate Compatible with any GC instrument Easy touch panel operation without PC Wizard function to navigate trough the operating procedure Sample is direct injected into the GC Equipped with electronic flow control (EPFC) Tube / liner size is industrie standard TD tube: 1/4 inch version (OD= ¼ x 3½ inch = 6.35 x 88.9 mm)
10-12-2020  |  074x  |  Product news  | 
Custom-built Spetec peristaltic pumps in the biotechnology sector For laboratory equipment Spetec offers costum-build peristaltic pumps for an enormous range of applications
Custom-built Spetec peristaltic pumps in the biotechnology sector
For laboratory equipment Spetec offers costum-build peristaltic pumps for an enormous range of applications Many different and varied pump types are in use both in technology in general and in daily life. These can be used to transport all types of materials. The most important pump types include piston pumps, centrifugal pumps, diaphragm pumps and peristaltic tube pumps. If these are used as part of a process, for example to transport fluids, then we speak about mechanical process engineering. In recent years, it has become ever more important to be able to meter fluid quantities in the microlitre range as biotechnology processes involving higher concentrations of active ingredients have come to the fore to respond to the need for process optimization. These demand high precision on the part of the employed pump technology, coupled with low pressure and volumetric flow pulsation, a high level of resistance against many different types of fluids, and the greatest possible service life. This pulsation-free metering of fluids by peristaltic pumps has been made possible, for
10-12-2020  |  085x  |  Product description  | 
CD Bioparticles Introduces Innovative Fluorescent Polymers
CD Bioparticles Introduces Innovative Fluorescent Polymers
As a leading manufacturer and supplier of various drug delivery products and services, CD Bioparticles now introduces a series of fluorescent polymers such as fluorescent dextrans, fluorescent heparins, and fluorescent alginates for potential applications in fluorescent nanoparticle/scaffold/hydrogel preparation, tracking and detection of cell uptake (e.g. macrophage), being able to conjugate with biomolecules for cell-specific and tissue-specific targeting, tracking, and detecting, and PK/PD analysis. With precise design and advanced technology platform, CD Bioparticles has a deep understanding of various delivery strategies and applications, which can help researchers get rid of tedious chemical synthesis, formulation, and purifications. CD Bioparticles can also help solve other challenges scientists might meet during the research, such as hard to track and image the distribution of the polymer based (nano-)materials, limited wavelength coverage for tracking and detection
09-12-2020  |  076x  |  Product news  | 
Creative Diagnostics Launches SARS-CoV-2 Magnetic Particles
Creative Diagnostics Launches SARS-CoV-2 Magnetic Particles
With years of experience in the pharmaceutical and life science sector, Creative Diagnostics recently introduces a series of SARS-CoV-2 magnetic particles for research applications in Immunoprecipitation and minimum protein purification, such as MagIso™ Anti-SARS-CoV/SARS-CoV-2 Spike S1 Magnetic Particles, MagIso™ Anti-SARS-CoV-2 (2019-nCoV) Spike Magnetic Particles Immunoprecipitation Kit, and Absolute Mag™ SARS-CoV-2 Spike S1 protein Conjugated Magnetic Particles. Included in the launch are the anti-Coronavirus spike magnetic particles, which are conjugated with anti-Coronavirus spike antibody, and are used for immuneprecipitation (IP) of Coronavirus spike proteins, expressed in vitro expression systems. For IP, the beads are added to a sample containing Coronavirus spike proteins to form a bead-protein complex. The complex is removed from the solution manually using a magnetic separator. The bound Coronavirus spike proteins are dissociated from the magnetic particles
09-12-2020  |  087x  |  Product news  | 
Vibration drive with round serial number manufactured by Vibrotechnik VP 30T № 5000 was produced and shipped to the customer
Vibration drive with round serial number manufactured by Vibrotechnik
VP 30T № 5000 was produced and shipped to the customer Vibrotechnik has sold the five thousandth copy of the VP 30 / VP 30T vibration drive. This model of sieving equipment is distinguished by exceptional reliability and high technical characteristics; some of those drives have been successfully operated by our customers for over 10 years. The buyer of VP 30T № 5000 is the Russian pharmaceutical company Ellara llc. Over the last month, 2 more models with round serial numbers were shipped to customers. JC 6M Jaw crusher № 1300 was supplied to Dels llc (Russia). DG 175M Disc grinder № 50 was purchased by Kaz altyn minerals llp (Kazakhstan).
08-12-2020  |  085x  |  Product news  | 
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