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CDD Awarded $1.5M Grant on an Intelligent Chemical Structure Browser Novel intelligent data browser to improve drug discovery efficiency
CDD Awarded $1.5M Grant on an Intelligent Chemical Structure Browser
Novel intelligent data browser to improve drug discovery efficiency Collaborative Drug Discovery (CDD), provider of CDD Vault web-based drug discovery informatics platform, announced they won a competitive, peer-reviewed Phase 2 SBIR grant from Nih ncats, titled: “Intelligent Chemical Structure Browser for Drug Discovery and Optimization”. This is a continuation of the Phase 1 project announced in 2019. CDD has developed a novel intelligent data browser that will enable medicinal chemists developing new drug compounds to more efficiently browse and organize experimental data in an intuitive way that – for the first time – matches how they mentally map the relationships among the closely similar molecules that comprise a chemical lead series. We estimate that our innovative approach will scale to thousands, and ultimately millions, of compounds in just a few minutes (on the same hardware), enabling us to create a delightful user experience that will present intuitive, automated chemical hyperlinking while hiding the internal complexity.
16-04-2021  |  007x  |  Industry news  | 
CDD Launches BioHarmony Semantic Drug Data Store A centralized semantic drug database for use across the entire discovery lifecycle
CDD Launches BioHarmony Semantic Drug Data Store
A centralized semantic drug database for use across the entire discovery lifecycle Collaborative Drug Discovery, Inc., provider of the CDD Vault informatics platform, recently launched BioHarmony, a drug data store that offers standardized data streams in real-time for any drug. Harmonized Drug Data Comprehensive drug information is harmonized and combined with user-friendly features to inform discovery, translational, and commercialization activities. BioHarmony provides data in AI-ready formats for holistic modeling. Real-Time Automated Data BioHarmony generates automated data streams that are updated daily and provided as a real-time annual subscription, ensuring that data is never outdated or inaccurate. Semantic Technology BioHarmony uses proprietary semantic web technology to extract, consolidate, and standardize data into a single centralized online information portal. Scalable Pricing BioHarmony`s flexible pricing structure enables scaling of data streams from single reports to an annual database subscription. Please visit our website
16-04-2021  |  008x  |  Product news  | 
CPhI Discover: event overview and highlights
CPhI Discover: event overview and highlights
 The last year has seen the pharma industry evolve its approach to meeting new partners and existing customers, using multiple avenues to meet new people with a wider pool of suppliers now needed. This has put a greater pressure on resources to find and evaluate partners before advancing discussions.  In response, we have launched CPhI Discover (17 – 28 May 2021), an annual dedicated online platform for pharma designed to encourage suppliers and customers to source, meet and discover – and will provide a complementary solution to CPhI’s existing portfolio of pharma events.   This ten-day event will play host to some 13,000+ attendees and over 570 companies, with three days of industry leading content consisting of over 20 keynotes, webinars and podcasts providing key insights in pharma from thought leaders. Additionally, CPhI Discover will also include five days of virtual meetings in week two, affording more time to meet greater numbers of potential suppliers, and
16-04-2021  |  009x  |  Industry news  | 
Built-in syringe pump Precision SY Developed for use in equipment where high precision in the microliter and nanoliter range is required
Built-in syringe pump Precision SY
Developed for use in equipment where high precision in the microliter and nanoliter range is required With its OEM syringe pump, Spetec presents a pump that permits ultra-precise metering of fluids in the range of microliters and nanoliters. The pump is adapted to suit the application in hand and is suitable for installation in the devices into which the fluids are to be fed. This could be for the purpose of analysis or filling or the addition of reagents. The stepper motor is coupled directly to the drive spindle, i.e. without gearing. This reduces mechanical play to a minimum. As a result, there is a direct correlation between the impulse applied and the delivery of the fluid. The value specified corresponds exactly to the absolute quantity to be delivered. The Spetec syringe pumps are remarkable for their high resolution of 25,600 steps per revolution and the barely discernible individual steps as the pump moves. A variety of precision syringes are employed for mixing or metering, but simple plastic syringes can also be used. Depending on the size and diameter of
15-04-2021  |  008x  |  Product description  | 
BOC Sciences Offers a Full Range of Fluorescent Reactive Dyes
BOC Sciences Offers a Full Range of Fluorescent Reactive Dyes
BOC Sciences recently updated its list of fluorescent dye products to further serve scientific research. And this series of products includes complete one-stop fluorescent reactive dyes. Fluorescent dyes have become a widely used fluorescent labeling tool because they have the advantages of fast detection speed, good repeatability, small sample volume, and no radiation. It is also used for scientific research in cell biology, immunology, biochemistry, microbiology, molecular biology, genomics, proteomics and neuroscience. The fluorescent dyes can be used to label target substances, determine the structure of cells, and distinguish nucleic acids in different conformations and the chemical reactivity of related drugs. Fluorescent reactive dyes, as differentiated functional dyes, have attracted more and more attention in the industry. Fluorescent reactive dyes are widely used to label biomolecules, such as antibodies, carbohydrates, nucleic acids, proteins, peptides and
15-04-2021  |  011x  |  Product news  | 
A New Discovered Special Cell Type Involved in The Neuropathic Pain
One of the main signs of chronic pain is inflammation. Recently, in a research report published in the international journal of Neuron, scientists from the University of North Carolina School of Medicine and other institutions have discovered through research that anti-inflammatory cells called MRC1+ macrophages may be dysfunctional in a mouse model of neuropathic pain. Promoting these cells to return to their normal state may be expected to help treat body pain caused by nerve damage or nervous system dysfunction. Researchers have shown that stimulating the expression of an anti-inflammatory protein called CD163 may reduce signs of neuroinflammation in the spinal cord of mice with neuropathic pain. Researchers have discovered that a type of anti-inflammatory macrophages may help relieve pain; but neuropathic pain seems to make these macrophages lose their function, but fortunately, they will not lose their function permanently. Because researchers can usually induce
15-04-2021  |  009x  |  Industry news
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