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Extra scrumptious tomatoes
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Extra scrumptious tomatoes

How is the growth and ripening of fruit regulated? That’s what researcher Ruud de Maagd at Wageningen Plant Research focuses on. The CRISPR-Cas system enables him to edit the genome much more precisely. “Basing our research on the tomato as a model fruit, we use CRISPR-Cas to inhibit certain genes, particularly transcription factors, to determine what their function is. In the past, we did this by means of spontaneous mutants or RNA interference. The dra- wback was that it was difficult to inhibit a gene completely or to inhibit one specific gene if there were several similar genes. CRISPR-Cas works much better and allows us to be far more precise,”

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